Hamdard Institute of Medical Sciences & Research (HIMSR)
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Research Projects Pharmacology

Research Projects-Pharmacology

 

  1. ICMR funded project “Pharmacological studies to evaluate the effects of Withania somnifera in experimental models of post-traumatic stress disorder (PTSD) and its mechanisms in rats”. (2019 -2021) PI: Prof A Ray, Co-Investigator: Dr. Sana Rehman– Rs. 34.0 lakhs – ongoing
  2. ICMR funded “Advanced Centre for Translational Research with Ayurvedic and Unani Medicinal Preparations in Respiratory and Allied Disorders.” (2018-2021) PI: Prof A Ray – 35.0 lakhs; ongoing
  3. Studies on the effects of Withania somnifera on airway inflammation and airway remodeling in experimental model of bronchial asthma (Ph.D thesis project of research scholar Nafaa Hasan Ali) (2018 – ongoing) PI: Prof A Ray, Co-Investigator: Dr. Sana Rehman (Self-Financed)
  4. Experimental Studies to Evaluate the Role Of Nitric Oxide (No) In Post-Traumatic Stress Disorder Induced Neurobehavioral And Cardiovascular Changes In Rats (MD thesis project of Dr Anuj Yadav) PI: Prof A Ray, Co-Investigator: Dr. Sana Rehman (2020-ongoing) (HIMSR)
  5. ’Evaluation of drug utilization with reference to national treatment guidelines and adverse event monitoring in intensive care units of a tertiary care teaching hospital: a prospective study (MD thesis project of Dr. Shamran Ahmad) PI: Prof A Ray, Co-Investigator: Dr. Shoma Mukherjee (2020-ongoing) (HIMSR)
  6. CCRUM (Ayush) Funded Project. “Experimental studies on the immunomodulatory and hepatoprotective effects of Dawa-Ul-Kurkum, a polyherbal Unani preparation, and its cellular and molecular mechanisms in rats.” (2017 – 2021) PI: Prof A Ray – 55.0 lakhs; ongoing
  7. ICMR approved Project. “A study to evaluate the pattern of antimicrobial utilization associated adverse events, biomarkers and treatment costs in Intensive Care Unit (ICU) Patients of a tertiary care teaching hospital.” (sanctioned; funding awaited) PI: Prof A Ray, Co-Investigator: Dr. Nusrat Nabi
  8. ICMR Funded Research Project Technically Approved– July 2020 titled “A Study to Evaluate the Treatment Outcome, Safety, Plasma Concentration and Quality Of Life of Bedaquiline Treatment in North Indian Patients of MDR TB”. Principal Investigator: Dr. Shoma Mukherjee.
  9. ICMR STS Project– Approved on June 2020 titled “A Drug Utilization Study and Safety Analysis of Psychotropic Drugs and its Impact on Quality of Life of Patients attending Psychiatry Outpatient Department of a Tertiary Care Teaching Hospital” Reference ID : 2020-08743. Guide: Dr. Shoma Mukherjee, Student: Arsh Arora. (Ongoing)
  10. Co- Supervisor in the Master Degree of Doctor of Medicine in Pharmacology, HIMSR, Jamia Hamdard, New Delhi on “Evaluation of Antibiotics with Reference to National Treatment Guidelines and Adverse Event Monitoring in Intensive Care Units of a Tertiary Care Teaching Hospital: A Prospective Study”. Guide-Prof. A Ray (Ongoing)
  11. Co- Supervisor in the PhD Degree of Medical Pharmacology, HIMSR, Jamia Hamdard, New Delhi on “A Comparative Clinical Study to Assess the Efficacy and Safety of Anti- anxiety Agents with respect to Clinical Manifestations and Disease Biomarkers in patients with Anxiety Disorders”. Guide- Prof. A Ray ( In process)
  12. Co-Supervisor, Master Degree of Pharmacy, School of Pharmaceutical Education and Research, Jamia Hamdard, 2016-2018. To assess knowledge, attitude and perception regarding antimicrobial use and resistance among the physicians, residents and final year medical students in a South Delhi teaching hospital. Supervisor: Prof. N. Saha.
  13. Co-Supervisor, Master Degree of Pharmacy, School of Pharmaceutical Education and Research, Jamia Hamdard, Nov 2015- 2017.To assess awareness of patients practicing Islam regarding lifestyle modification and medication alteration of antidiabetic during Ramadan: A survey. Supervisor: Prof. N. Saha.
  14. Co- Investigator in STS- Project on “Effect of Phlorizin, a SGLT-1 inhibitor, alone and in combination with Metformin on glucose transport in everted sac model of rat intestine”. (Reference ID: 2016- 02720). Principal Investigator: Prof. N Saha, Department of Pharmacology, HIMSR, 2016.
  15. Co- Supervisor – Ph.D. Degree in Pharmaceutical Medicine: June 2013 – 2015. Evaluation of oral bioavailability of Xolstat 20mg tablets (containing rosuvastatin calcium equivalent to rosuvastatin 20mg) of Ranbaxy Laboratories Limited in comparison with Crestor 20mg tablets (containing rosuvastatin calcium equivalent rosuvastatin 20mg) of IPR Pharmaceuticals Inc. and to assess the safety profile in healthy adult human subjects under fasting condition.
  16. BA/BE Studies: Independently conducted around 500 healthy volunteer BA/BE studies as Principal Investigator & Senior Research Scientist from 2012 to Jan 2015.
  17. Multicentric Global Clinical trial experience as Medical Monitor:
  18. Phase III Trial – Randomized, open –label study of xxx in subjects with Chemotherapy Induced Anaemia.
  19. Phase III Trial- Randomized, comparative, open –label study of intravenous xxx in patients with Non-Dialysis Dependent Chronic Kidney Disease and with Renal – Related Anaemia.
  20. A Phase III, randomized, comparative, open- label study of intravenous xxx in inflammatory bowel disease subjects with iron deficiency anaemia
  21. Phase II Trial – To evaluate the safety, tolerability and efficacy of xxx to patients with colorectal adenocarcinoma previously untreated for metastatic disease.
  22. Phase IV Study – A multicenter, prospective, open label study of the safety and efficacy of xxx in Indian patients with symptomatic osteoarthritis of the knee (s) after initial and repeat treatment.
  23. Phase II Trial- Randomized, prospective, double blind, parallel group, multicenter study to determine safety and efficacy of xxx in treatment of Venous Leg Ulcer.
  24. Phase II Trial Randomized, prospective, double blind, parallel group, multicenter study to determine safety and efficacy of xxx in treatment of Diabetic Foot Ulcer.
  25. Phase II Trial – Randomized, prospective, double blind, parallel group, multicenter study to determine safety and efficacy of xxx in Laparoscopic scar.
  26. Phase II Trial – A prospective, randomized, placebo- controlled study to evaluate the effect of xxx in the management of advanced cancer cervix
  27. Phase II Trial – Randomized, comparative, open- label study of xxx in subjects with Stage 5 Chronic kidney Disease on Dialysis Therapy (CKD- 5D).
  28. Phase I/II/III – Pharmacokinetic and outcome study of xxx in subjects with Hemophilia B
  29. Phase III Trial – Study of xxx in previously treated pediatric subjects with Hemophilia B
  30. A Comparative Study on the Effect of a Statin, Felodipine and Propranolol on Serum Lipid Profile, Creatinine and Blood Glucose Level of Rabbits. M.D Research Work 2002- 2005, Department of Pharmacology, Gauhati Medical College, Guwahati .Supervisor: Prof. M. Lahkar.
  31. ICMR funded research project on “Pharmacological studies to evaluate the effects of Withania somnifera in experimental models of post-traumatic stress disorder (PTSD) and its mechanisms in rats” – from 2019 – 2021 (ongoing) PI: Prof A Ray, Co-Investigator: Dr. Sana Rehman– Rs. 34.0 lakhs
  32. Co-Supervisor in degree of master of science (medical physiology) hamdard institute of medical sciences and research jamia hamdard, new delhi (2020-2021). To study the analgesic & anti-inflammatory activity of l-arginine on albino mice. Guide-Dr. Alam, Co-investigator: Dr. Sana Rehman.
  33. Co-Supervisor in degree of master of science (medical physiology) hamdard institute of medical sciences and research jamia hamdard, new delhi (2020-2021). To study the antidepressent effect of plant product on albino rat. Guide-Dr. Alam, Co-investigator: Dr. Sana Rehman.
  34. Co-investigator in the master degree of doctor of medicine in pharmacology, HIMSR, Jamia Hamdard, New Delhi on “Experimental studies to evaluate the role of nitric oxide (no) in post-traumatic stress disorder induced neurobehavioral and cardiovascular changes in rats”. Guide-Prof. A Ray, Co-investigator: Dr. Sana Rehman.
  35. Co-Supervisor in the master degree of medicine in Dept. of Ilmul Advia (Pharmacology lab), SUMER, jamia hamdard, New delhi (2019-2022). Experimental Studies on the Anti-stress effect of Majoon Barhami and Optimization of the Formulation in experimental models. Guide: Prof M.A Jafri, Co-investigator: Dr. Sana Rehman.
  36. Experimental Studies to Evaluate the Role Of Nitric Oxide (No) In Post-Traumatic Stress Disorder Induced Neurobehavioral And Cardiovascular Changes In Rats (MD thesis project of Dr Anuj Yadav) PI: Prof A Ray, Co-Investigator: Dr. Sana Rehman (2020-ongoing) (HIMSR)

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