Research Projects HIMSR

HIMSR & HAHCH ONGOING RESEARCH PROJECTS  2020-2021

 

 DEPARTMENT OF PHYSIOLOGY

 

1. To Study the effect of inspiratory muscle training in hypercapnic COPD patients during acute care under Prof Iqbal Alam (Tabassum Saher, JRF-UGC )
2. Cognitive Remediation through Behavioural Reinforcement in Traumatic Brain Injury (Co-PI) Sponsored by Core Research Grant SERB-DST (File Number: CRG/2020/003832)
3. An epidemiological study to assess household transmission & associated risk factors for COVID-19 disease amongst residents of Delhi, India. (This protocol is aligned with the WHO Unity protocol on household transmission protocol for COVID-19) WHO sponsored project (Co-PI Prof Iqbal Alam)
4. Early Detection of Bio-markers for pre-eclampsia, Grand Challenges Canada Grant Number:R-ST-POC-1807-13914, (amount of $94.889 CAD).
5. Characterization of sterile inflammatory biomarkers for the development of preeclampsia and its pathogenesis. (Huma Quasimi, SRF, Sponsored by ICMR)
6. To study the genetic polymorphism of Matrix – metalloproteinase-2 and its association with the oxidative stress biomarkers in COPD in North-Indian Population. DST-Inspire (DST/INSPIRE/03 /2017/001003) (Poonam Sangwan, JRF-DST-Inspire)

 

DEPARTMENT OF BIOCHEMISTRY

 

1. Assessment of the role of Unani formulations in the prevention of COVID- 19 infection in high-risk population (Project approved by Ministry of AYUSH and sponsored by M/S Hamdard Laboratories India (Medicine Division). -Co PI Dr Kailash
2. 2020- Short term studentshipprogram(STS), by The Indian Council of Medical Research (ICMR); Project titled “Study analyzing the possible role of glycated DNA in the pathophysiology of Pre-diabetes” (Reference ID 2020 – 10272), Guide- Dr. Sana Alam,)
3. 2020- Intramural project titled “Utility of hematological & biochemical parameters as a screening tool for assessing COVID-19 infection and its severity( Co-investigator- Dr Sana Alam)

 

 

DEPARTMENT OF PATHOLOGY

 

1.”Study of saphenous vein graft in diabetics and non diabetics with coronary artery disease & its correlation with damage associated molecular pattern proteins” (ICMR project, funding 65lakh)- PI prof Sujata Jetley,Co PIi- Dr Zeeba Jairajpuri)

2. Cytological evaluation of a unani formulation with inkebab (medicated inhalation) in the treatment of iltehab tajaweefe anaf muzmin (chronic rhinosinusitis) ( PI –Dr. Zehra Zaidi, Co-PI- Prof Sabina Khan )
3. Utility of haematological and biochemical parameters as a screening tool for assessing COVID-19 infection and its severity ( PI- Prof Sabina Khan)
4. Relationship between insulin resistance and hematological parameters in semi urban pre-diabetic population of South Delhi: An emerging link (Co-PI Prof Sabina Khan )

5.Helicobacter pylori infection in Gallbladder Tissue and its association with Cholelithiasis (Co-PI- Prof Sabina Khan )

 

DEPARTMENT OF PHARMACOLOGY

 

1. ICMR funded project “Pharmacological studies to evaluate the effects of Withania somnifera in experimental models of post-traumatic stress disorder (PTSD) and its mechanisms in rats”. (2019 -2021) PI: Prof A Ray, Co-Investigator: Dr. Sana Rehman– Rs. 34.0 lakhs
2. ICMR funded “Advanced Centre for Translational Research with Ayurvedic and Unani Medicinal Preparations in Respiratory and Allied Disorders.” (2018-2021) PI: Prof A Ray – 35.0 lakhs.
3. CCRUM (Ayush) Funded Project. “Experimental studies on the immunomodulatory and hepatoprotective effects of Dawa-Ul-Kurkum, a polyherbal Unani preparation, and its cellular and molecular mechanisms in rats.” (2017 – 2021) PI: Prof A Ray – 55.0 lakhs
4. ICMR approved Project. “A study to evaluate the pattern of antimicrobial utilization associated adverse events, biomarkers and treatment costs in Intensive Care Unit (ICU) Patients of a tertiary care teaching hospital.” PI: Prof A Ray, Co-Investigator: Dr. Nusrat Nabi
5. To evaluate the effect of natural bioactive compounds in chemically induced Parkinson Disease in rats (in progress) PI: Prof Razi Ahmad
6. Evaluation of effect of natural bioactive compounds on Cecal ligation and puncture induced sepsis in rat (in progress) PI: Prof Razi Ahmad
7. ICMR approved – July 2020. “A Study to Evaluate the Treatment Outcome, Safety, Plasma Concentration and Quality of Life of Bedaquiline Treatment in North Indian Patients of MDR TB”. PI: Dr. Shoma Mukherjee, Co- PI: Prof. A. Ray.
8. ICMR STS Project. “A Drug Utilization Study and Safety Analysis of Psychotropic Drugs and its Impact on Quality of Life of Patients attending Psychiatry Outpatient Department of a Tertiary Care Teaching Hospital” Reference ID: 2020-08743. Approved on June 2020. Guide: Dr. Shoma Mukherjee.
9. “Experimental Studies on the Anti-stress effect of Majoon Barhami and Optimization of the Formulation in experimental models. in Dept. of Ilmul Advia (Pharmacology lab), SUMER, Jamia Hamdard (2019-2022).Guide: Prof M.A Jafri, Co-Investigator: Dr. Sana Rehman

 

DEPARTMENT OF MICROBIOLOGY  

 

1. ‘Assessment of the role of Unani formulations in the prevention of COVID-19 infection in high-risk population’ (Project approved by Ministry of AYUSH and sponsored by M/S Hamdard Laboratories India (Medicine Division ) PI- Prof Mridu Dudeja: Co PI-  Dr. Ayan Kumar Das
2. Assessment of Potential Risk Factors for COVID-19 among Health Care Workers in a Health Care Setting in Delhi, India. PI Prof Mridu Dudeja, Co-PI Neetu Shree, Dr. Mehvash: Dr. Shyamasree: WHO Funded Project
3. An epidemiological Study to Assess Household Transmission & Associated Risk Factors for COVID-19 Disease amongst Residents of Delhi, Co-PI Prof Mridu Dudeja, Dr. Ayan Kumar Das.WHO Funded Project
4. Effectiveness of Covaxin and Covishield vaccines against severe COVID-19 in India, 2021: Multi-centric hospital-based case control study ICMR-NIE and WHO Project (CoPI-Prof Mridu Dudeja)

 

DEPARTMENT OF COMMUNITY MEDICINE

 

1. Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multi-Centre Phase II/III Adaptive Clinical Trial to Assess the Safety and Immunogenicity of Gam-COVID-Vac Combined Vector Vaccine for SARS-Сov-2 Infection in Indian Healthy Subjects (PI –Dr Aqsa Sheikh, Rs 30 lakh funding)
2.  Quality of life, treatment seeking pathways and out of pocket expenditure of parents with Autism Spectrum Disorder (ASD) in South Mentor: Dr Farzana Islam 2020 ICMR STS
3. Community based Sero-surveillance and incidence of Dengue among residents of South Delhi, India PI – Farzana Islam. Co-PI: Dr. Meely Panda, Dr. Aqsa Shaikh, Dr. Faheem Ahmed Dr. Rashmi Agarwalla Dr. Ekta Gupta 2020 THSTI Funded
4. Cross-sectional study to assess perception and proportion of sexual harassment among working women in health sector of India – An exploration of Facts PI – Meely Panda2020 ICMR 5 Lakhs
5. An interventional study to assess impact of behaviour modification therapy versus brief advise for tobacco cessation among adult tobacco users residing in a resettlement colony of Delhi PI – Dr. Rashmi Agarwalla2020 ICMR 8 Lakhs
6. Assessment of Potential Risk Factors for COVID – 19 among Health Care Workers in a Health Care Setting in Delhi, India Co-Investigators: Prof Farzana Islam, Dr Aqsa Shaikh, Dr Meely Panda, Dr. Yasir Alvi 2020 WHO Funded Approved
7. An epidemiological study to assess household transmission and associated risk factors for COVID – 19 Disease among residents of Delhi, India PI – Farzana Islam, Co-PI: Dr. S. Roy, Dr. Faheem Ahmed, Dr. Rashmi Agarwalla, Dr. Ekta Gupta, Dr. Meely Panda2020 WHO Funded Yet to start Dr Farzana Islam, Dr Aqsa Shaikh, Dr Yasir, Dr. Rashmi, Ekta Gupta
8. An interventional study to assess impact of behaviour modification therapy versus brief advise for tobacco cessation among adult tobacco users residing in a resettlement colony of Delhi, Ongoing, ICMR (2020)  PI- Dr Farzana Islam, Co PI-Dr Yasir Alvi,  Dr Ekta Gupta, Dr Ayan
9. A cross-sectional study to assess perception and proportion of sexual harassment among working women in health sector of India – An exploration of facts. ICMR (2020)- PI- Dr Farzana Islam, Co PI-Dr Yasir Alvi,
10. Effectiveness of Covaxin and Covishield vaccines against severe COVID-19 in India, 2021: Multi-centric hospital-based case control study ICMR-NIE and WHO Project (PI Dr Faheem Ahmad, Co PI -DrFarzana, Dr Yasir)

 

DEPARTMENT OF GENERAL MEDICINE

 

1. A Phase 2/3, Randomized, Observer-blind, Controlled, Multi-Center Study to Evaluate the Lot to Lot Consistency of SIIPL Meningococcal ACYWX Conjugate Vaccine (NmCV- 5) and to Compare its Safety and Immunogenicity with that of Licensed Meningococcal ACWY Vaccine Menactra®️ in Healthy Individuals 18-85 Years of Age Phase 3 trial for Meningococcal vaccine (ACYWX conjugate vaccine, NmCV- 5) in adult population. (Sponsor-SIIPL,PI- Dr Sunil Kohli)
2. Covid vaccine – RDI-GCV-001 Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multi-Centre Phase II/III Adaptive Clinical Trial to Assess the Safety and Immunogenicity of Gam-COVID-Vac Combined Vector Vaccine for SARS-Сov-2 Infection in Indian Healthy Subjects (Sponsor-DRL,PI- Dr Sunil Kohli)
3. Covid vaccine – ICMR/SII-COVOVAX.A phase 2/3, observer-blind, randomized, controlled study to determine the safety and immunogenicity of COVOVAX [SARS-CoV-2 recombinant spike protein nanoparticle vaccine (SARS-CoV-2 rS) with Matrix-M1™adjuvant] in Indian adults (Sponsor-ICMR-NARI,SIIPL; PI- Dr Sunil Kohli)

 

DEPARTMENT OF PEDIATRICS      

 

1. Phase 3, Randomized, Double-Blind Study to Evaluate the Immunogenicity, Safety and Tolerability of Serum Institute of India’s 10-Valent Pneumococcal Conjugate Vaccine (Pneumosil^®) In Healthy Indian Infants (PI- Dr Nidhi Bedi)
2. An Open Label, Randomized, Active Controlled, Multi-Centric Phase Ii/Iii Study In Indian Toddlers And Infants To Assess The Immunogenicity And Safety Of Siipl Hexasiil™ (Dtwp-Hepb-Ipv-Hib) Vaccine In Comparison With Siipl Pentavac (Dtwp- Hepb-Hib) + Poliovac (Ipv) Vaccines, Administered As Separate Injections (Sii- Whexa-In/02). (PI- Dr Aparna Chakraborty)
3. Uncovering the Genetics of Novel Salmonella Typhi Strains from Delayed Responders to Treatment (ICMR  Proposal Id- 2020-2800) ICMR Funding- 50 Lakhs ( Co PI- Dr Aparna Chakraborty)
4. A Seamless Phase Ii/Iii, Double-Blind, Multi-Centre, Randomized Clinical Trial to Evaluate Immunogenicity And Safety of Bbv87, An Inactivated Chikungunya Virus Vaccine in Healthy Subjects 12-65 Years of Age- Sponsor DBT-BBIL ( Co PI- Dr Aparna Chakraborty)
5. Protective and Pathogenic Immunity in Dengue Virus Infection in collaboration with Jamia Hamdard- Institute of Molecular Medicine (Co PI- Dr Aparna Chakraborty)

 

DEPARTMENT OF PSYCHIATRY  

 

1. ‘An interventional study to assess impact of behavior modification therapy versus brief advise for tobacco cessation among adult tobacco users residing in a resettlement colony of ICMR funded project- (Co- PI Dr Rashmi Prakash)
2. COVID-19 Pandemic: Assessment of anxiety status and perception of E – learning amongst first year undergraduate medical students. ( Co PI Dr Rashmi Prakash)

 

DEPARTMENT OF RESPIRATORY MEDICINE 

 

1.  “Molecular Diagnosis of MTB Using Signature Sequences of Mycobacterium Tuberculosis.”  (Co PI-Dr Sameera Banday)
2. Co-Investigator collaborating with the Department of Microbiology and Unani Medicine on project entitled “Assessment of the role of Unani formulations in the prevention of COVID-19 infection in high-risk population.” ( Co- PI- Dr Sameera Banday )

 

 

DEPARTMENT OF GENERAL SURGERY   

 

1.  Assessment of perception of patient safety culture among health care workers in a tertiary care center. (PI. Dr. Musharraf Husain )
2. Association of  Helicobacter pylori in Gallbladder Tissue with Cholelithiasis: A prospective study  in a tertiary care centre  in Delhi.  Co PI. Dr. Musharraf

3. Prophylactic antibiotic in elective laparoscopic Cholecystectomy. A prospective randomized study. (Principal Investigator: Dr. Musharraf Husain, Co-P: Dr.Tajamul Rashid)
4. Study of Histopathological correlation of endoscopic findings in Chronic gastritis in a sample Indian population. (Co-PI: Dr. Musharraf Husain)

 

DEPARTMENT OF OPHTHALMOLOGY   

 

Intraocular pressure changes following laryngoscopy & tracheal intubation with Macintosh laryngoscope (King Vision) in non-ophthalmic surgeries: A Randomized (Ongoing, Co PI-Dr Taskin Khan)

 

DEPARTMENT OF OBSTETRICS AND  GYNAECOLOGY

 

1. ‘Assessment of Sympathetic Vascular Reactivity in Pregnant women using Cold Presser test & Heart Rate variability’ PI. Dr. Neha Gupta
2. To study the role of non sterile and inflammatory molecules in Preeclamptic patients-STS-ICMR Project , PI -Dr Arifa Anwar
3. Comparative study on effectiveness of combination of mifepristone & misoprostol with only misoprostol in missed abortion-  PI Dr. Nidhi Gupta
4. A survey on presenting complaints and contraceptive knowledge of adolescent girls attending the HAHC Hospital- PI Dr. Nidhi Gupta
5. Covid-19 and pregnancy: feto-maternal outcome- PI Dr. Nidhi Gupta

 

 

 

DEPARTMENT OF ANAESTHESIOLOGY   

 

1. A study of patient’s knowledge and awareness of patient factors influencing perioperative risks and their perception of their participation in enhancing their own perioperative (Institutional ethics committee Jan 2020) PI. Dr. Irshad
2. Correlation of preoperative IVC collapsibility with preoperative fasting status, patient demography and general anaesthesia induced hypotension: a prospective observational study (HIMSR / IEC/005/2020) PI Dr. Jyotsna
3. Intraocular pressure changes following laryngoscopy & tracheal intubation with Macintosh laryngoscope (King Vision) in non-ophthalmic surgeries: A Randomized study . PI Dr. Samiksha
4. Post-operative Pain relief after laparoscopic cholecystectomy: Intraperitoneal ropivacaine V/s Nalbuphine.Current practice of Rapid Sequence Induction (RSI) in paediatric Anaesthesia: A survey from Dr. Samiksha
5. Evaluation of effect of N95 filtering face piece respirator on hypercapnic response & hemodynamic changes in health care worker – a prospective study. PI. Dr. Sana
6. Comparative evaluation of landmark technique and ultrasound guided caudal epidural injection in paediatric population: systematic review & metanalysis- PI Dr Sana Yasmin

 

DEPARTMENT OF DENTISTRY  

 

1. Fabrication and Multicentric Trial of Indigenous Dental Implants of Titanium Designed and Developed at BHU for it’s Validation(Co PI-Dr Nilima Sharma).
2. To evaluate the effect of oral health lecture on knowledge, attitude and practice among group d employees of a tertiary care hospital in New Delhi: a cross sectional study.(PI: Dr. Chavi Jain, Co PI- Dr Nilima Sharma)
3. Knowledge, attitude and practices among medical graduates, post graduates, junior and senior faculties regarding artificial intelligence (AI) and machine learning (MI) of a private medical college of New Delhi: a cross sectional observational comparative study.(PI: Dr. Chavi Jain, Co PI- Dr Nilima Sharma)
4. Cross sectional study to assess prevalence of risk factors and knowledge of hepatitis B among patients attending health care centres of a tertiary level institute in New Delhi, India. In collaboration with Faculty of Unani Medicine (PI: Dr. Akbar Naqvi, Co PI- Dr Nilima Sharma) )